Detalhe da pesquisa
1.
Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.
Cell
; 177(3): 597-607.e9, 2019 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002796
2.
Common and rare variant associations with clonal haematopoiesis phenotypes.
Nature
; 612(7939): 301-309, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36450978
3.
Exome sequencing and analysis of 454,787 UK Biobank participants.
Nature
; 599(7886): 628-634, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34662886
4.
Divergent role of Mitochondrial Amidoxime Reducing Component 1 (MARC1) in human and mouse.
PLoS Genet
; 20(3): e1011179, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38437227
5.
Activin E-ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice.
Proc Natl Acad Sci U S A
; 120(32): e2309967120, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37523551
6.
Germline Mutations in CIDEB and Protection against Liver Disease.
N Engl J Med
; 387(4): 332-344, 2022 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35939579
7.
Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes.
Nature
; 615(7950): E3, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36807635
8.
Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length.
Am J Hum Genet
; 106(3): 389-404, 2020 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32109421
9.
Genome-wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals.
Genet Epidemiol
; 45(6): 664-681, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34184762
10.
Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes.
Circ Res
; 126(3): 330-346, 2020 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31739742
11.
Patients With High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit From Alirocumab Treatment in the ODYSSEY OUTCOMES Trial.
Circulation
; 141(8): 624-636, 2020 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31707832
12.
Genome-Wide Polygenic Score, Clinical Risk Factors, and Long-Term Trajectories of Coronary Artery Disease.
Arterioscler Thromb Vasc Biol
; 40(11): 2738-2746, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32957805
13.
The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.
PLoS Med
; 17(10): e1003394, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33064751
14.
The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies.
Am J Epidemiol
; 188(6): 991-1012, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31155658
15.
Genomic insights into the causes of type 2 diabetes.
Lancet
; 391(10138): 2463-2474, 2018 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29916387
16.
Complications of whole-exome sequencing for causal gene discovery in primary platelet secretion defects.
Haematologica
; 104(10): 2084-2090, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30819905
17.
Whole-exome sequencing to identify genetic risk variants underlying inhibitor development in severe hemophilia A patients.
Blood
; 127(23): 2924-33, 2016 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27060170
18.
Prioritising Risk Factors for Type 2 Diabetes: Causal Inference through Genetic Approaches.
Curr Diab Rep
; 18(7): 40, 2018 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29779155
19.
Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.
JAMA
; 320(24): 2553-2563, 2018 12 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30575882
20.
Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.
PLoS Med
; 13(11): e1002179, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27898682